- Mediocre college student Yūya Nomoto encounters a mysterious girl named Hitomi after his acquaintances ask him to drive them around to pick up girls one day, which he soon finds out means by force. Hitomi slaughters all of them except Yūya, who is shocked to see her transform into a beast and battle a lion monster at an abandoned waste facility. These strange people are "Brutes", fighters that have been created to combine the brains of humans and the fangs of beasts with powerful businesses betting on the outcome of their duels. Hitomi is a honey badger, which has been called the most fearless of all animals and is assigned to stay with Yuuya, for his protection. The "Killing Bites" battles have also been the decisive turning points in the Japanese economy since ancient times.