- At the start of the 21st century, an interplanetary war broke out. Earth's ecosystem was severely damaged, and humanity was forced to flee the planet. In several planets of this new society, things that "disturb the heart" like music and art are forbidden. 48 years later, the legendary idol group AKB48 is resurrected as the interplanetary troupe AKB0048, made up of girls who carry on the title and spirit of the original members. Held as heroines by some and labeled as terrorists by others, they must take up arms to bring their music to their fans wherever they are. The story follows a group of young hopefuls as they train to become the next generation of AKB0048.